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5-FLUORO-1,3-DIMETHYLURACIL

Product Name
5-FLUORO-1,3-DIMETHYLURACIL
CAS No.
3013-92-1
Chemical Name
5-FLUORO-1,3-DIMETHYLURACIL
Synonyms
Fluorouracil-001;Fluorouracil Impurity 34;1,3-dimethyl-5-fluorouracil;5-FLUORO-1,3-DIMETHYLURACIL;5-Fluoro-1,3-dimethyluracil 99%;5-fluoro-1,3-dimethylpyrimidine-2,4-dione;5-fluoro-1,3-diMethylpyriMidine-2,4(1H,3H)-dione;2,4(1H,3H)-Pyrimidinedione,5-fluoro-1,3-dimethyl-;1,3-Dimethyl-5-fluorouracil, 2,4-Dihydroxy-1,3-dimethyl-5-fluoropyrimidine
CBNumber
CB8116404
Molecular Formula
C6H7FN2O2
Formula Weight
158.13
MOL File
3013-92-1.mol
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5-FLUORO-1,3-DIMETHYLURACIL Property

Melting point:
132-134 °C(lit.)
Boiling point:
182.5±50.0 °C(Predicted)
Density 
1.37±0.1 g/cm3(Predicted)
pka
-4.07±0.40(Predicted)
BRN 
880396
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
406864
Product name
5-Fluoro-1,3-dimethyluracil
Purity
99%
Packaging
10g
Price
$151
Updated
2023/06/20
AK Scientific
Product number
1409AQ
Product name
5-Fluoro-1,3-dimethyluracil
Packaging
10g
Price
$212
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
NUC0002048
Product name
5-FLUORO-1,3-DIMETHYLURACIL
Purity
95.00%
Packaging
10G
Price
$1219.42
Updated
2021/12/16
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5-FLUORO-1,3-DIMETHYLURACIL Chemical Properties,Usage,Production

Uses

5-Fluoro-1,3-dimethyluracil may be used as starting material in the following processes:

  • Regioselective synthesis of tetrahydronaphthocyclobuta[1,2-d]pyrimidinediones.
  • To synthesize 5-bis(ethoxycarbonyl)methyl-1,3-dimethyluracil.
  • To synthesize new highly conjugated propenylidene derivatives via aromatic Paterno-Buchi type cycloaddition with 1-methoxynaphthalene.

Synthesis Reference(s)

Tetrahedron, 46, p. 3093, 1990 DOI: 10.1016/S0040-4020(01)88400-3

General Description

Oxidation of 5-fluoro-1,3-dimethyluracil (5-FDMU) with m-chloroperbenzoic acid has been described. It is reported as antineoplastic drug. On photoirradiation, 5-fluoro-1,3-dimethyluracil yields the trans-anti cyclobutane dimer and the cis-syn cyclobutane dimer. UV irradiation of 5-FDMU and naphthalene in a protic medium affords 5-(1-naphthyl)uracil, while in aprotic media it undergoes stereoselective 1,4-cycloaddition reaction to give a barrelene derivative. The thermochemical parameters of 5-FDMU has been determined. It reacts with substituted benzenes in the presence of trifluoroacetic acid to generate 5-aryl-1,3-dimethyluracils via photosubstitution.

5-FLUORO-1,3-DIMETHYLURACIL Preparation Products And Raw materials

Raw materials

Preparation Products

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5-FLUORO-1,3-DIMETHYLURACIL Suppliers

Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57511
Advantage
58
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View Lastest Price from 5-FLUORO-1,3-DIMETHYLURACIL manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Fluorouracil-001 3013-92-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2020-05-14

3013-92-1, 5-FLUORO-1,3-DIMETHYLURACILRelated Search:


  • 1,3-Dimethyl-5-fluorouracil, 2,4-Dihydroxy-1,3-dimethyl-5-fluoropyrimidine
  • 5-fluoro-1,3-diMethylpyriMidine-2,4(1H,3H)-dione
  • 5-FLUORO-1,3-DIMETHYLURACIL
  • 1,3-dimethyl-5-fluorouracil
  • 2,4(1H,3H)-Pyrimidinedione,5-fluoro-1,3-dimethyl-
  • Fluorouracil-001
  • 5-Fluoro-1,3-dimethyluracil 99%
  • 5-fluoro-1,3-dimethylpyrimidine-2,4-dione
  • Fluorouracil Impurity 34
  • 3013-92-1
  • Building Blocks
  • Heterocyclic Building Blocks
  • Pyrimidines